The hot water extract of a mixture of Anogeissus leiocarpus (Combretaceae) and Proso- pis africana (Mimosaceae) is widely used in the northern part of Nigeria for the treatment and management of asthma. Preliminary investigations of its pharmacological activities

pis africana (Mimosaceae) is widely used in the northern part of Nigeria for the treatment and management of asthma. Preliminary investigations of its pharmacological activities justify its use in folk medicine (1). Urgent need for the development of systems and methods for standardization of traditional medicine has led to the formulation of the extract into tablets using the wet granulation method of massing and screening. Many compaction techniques have been used to characterize the consolidation behavior of pharmaceutical solids (2, 3). However, due to the complexity of the compression process, many of the expressions used were shown to have limitations. A simple and most widely used approach is the analysis of the Heckel plots. Although the Heckel